Prevention of abdominal wound infection: PROUD-Trial A randomized controlled trial

Conditions

elective midline laparotomy

Diener MK, Knebel P, Kieser M, Schüler P, Schiergens TS, Atanassov V, Neudecker J, Stein E, Thielemann H, Kunz R, von Frankenberg M, Schernikau U, Bunse J, Jansen-Winkeln B, Partecke LI, Prechtl G, Pochhammer J, Bouchard R, Hodina R, Beckurts KT, Leißner L, Lemmens HP, Kallinowski F, Thomusch O, Seehofer D, Simon T, Hyhlik-Dürr A, Seiler CM, Hackert T, Reissfelder C, Hennig R, Doerr-Harim C, Klose C, Ulrich A, Büchler MW.

2014-04-07124 citations

10.1016/s0140-6736(14)60238-5

Prevention of abdominal wound infection (PROUD trial, DRKS00000390): study protocol for a randomized controlled trial.

Heger U, Voss S, Knebel P, Doerr-Harim C, Neudecker J, Schuhmacher C, Faist E, Diener MK, Kieser M, Seiler CM, Büchler MW.

2011-11-2110 citations

10.1186/1745-6215-12-245

Interventions

Group 1: The abdomen will be closed by a continuous, all-layer suture using two loops of slowly absorbable monofilament suture =PDS II plus (coated with triclosan). Group 2: The abdomen will be closed

Eligibility

Sex/Gender

All

Age

18 Years to 100 Years

Inclusion criteria

Inclusion criteria: age >= 18 years/ Patients undergoing elective midline laparatomy / Informed consent

Exclusion criteria

Exclusion criteria: Participation in another intervention-trial with interference of intervention and / or outcome of this study / Impaired mental state or language problems

Design outcomes

Primary

Measure	Time frame
Wound infection (deep and superficial according to CDC definition) within 30 days after surgery	—

Secondary

Measure	Time frame
Duration of surgery / Length of incision / Frequency of wound dehiscence (with or without evisceration) / Frequency of re-operation due to wound dehiscence / Postoperative intensive care unit stay / Postoperative hospital stay / 30 day mortality / Quality of life (QoL)	—

Countries

Germany

Contacts

Public ContactColette Dörr-Harim

Chirurgische Universitätsklinik Heidelberg Studienzentrum der Deutschen Gesellschaft für Chirurgie-SDGC

colette.doerr-harim@med.uni-heidelberg.de+49 6221 56 6986

Outcome results

None listed