Correlation of clinical outcome with intraarticular cytokine concentrations following cartilage regeneration in knee and upper ankle joint

Correlation of clinical outcome with intraarticular cytokine concentrations following cartilage regeneration in knee and upper ankle joint - CORRCYT

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00000365

Enrollment

100

Registered

2010-03-08

Start date

2009-08-30

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

M93.2 M94.26

Interventions

None listed

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: performance of an arthroscopy of the knee joint or the upper ankle joint, patients in the control group have no cartilage lesion in MRI and diagnostic arthroscopy, patients undergoing microfracturing or ACI have full thickness cartilage lesions graded III and IV according to ICRS classification of various size, agreement to participate in the study, age >18 years and <65 years

Exclusion criteria

Exclusion criteria: alcohol or drug abuse, mental retardation with incapability to complete the necessary self-reports, joint effusion >30ml, persistent knee oder upper ankle joint instability, infection

Design outcomes

Primary

Measure	Time frame
Lysholm Score, IKDC Score: validated scores about knee function	—

Secondary

Measure	Time frame
Noyes Score, the Medical Outcomes Study Short Form-36 (SF-36), and visual analog scales (VAS) for knee pain strength and frequency: parameter for life quality	—

Countries

Germany

Contacts

Public ContactHagen Schmal

Universitätsklinik Freiburg Dep. Orthopädie und Traumatologie

hagen.schmal@uniklinik-freiburg.de0761 270 9016/2401

Outcome results