Gender Differences in Aortic Stenosis II

Gender Differences in Aortic Stenosis II - GUAS II

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00000340

Enrollment

Registered

2010-03-15

Start date

2010-08-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I35.0

Interventions

Group 1: after informed consent, a tissue sample from LV myocardium is obtained during surgery from all patients with signifcant LV outflow tract obstruction

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: AS II-IV Patients in need of surgery,> 18 Yrs, consent after oral and written information and agreement

Exclusion criteria

Exclusion criteria: Coronary heart disease, hemodynamically effective congenital heart defects, or additional cardiovascular disease in addition to aortic stenosis, malignant systemic diseases

Design outcomes

Primary

Measure	Time frame
myocardial Genex epression. arbitrary units; intra - surgery, by PCR \|\| myocardial Genex epression. arbitrary units	—

Countries

Germany

Contacts

Public ContactVera Regitz-Zagrosek

Institut für Geschlechterforschung in der Medizin, Charite und DHZB

vera.regitz-zagrosek@charite.de+49 30 4593 2410 oder +49 30 450 525172

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026