Periodontal changes during pregnancy with and without risk for preterm delivery

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00000282

Enrollment

150

Registered

2009-12-09

Start date

2010-08-11

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

periodontal changes

Interventions

None listed

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Study group 1: Singleton pregnancy before 32nd week of gestation, in-patient due to risk for preterm delivery Study group 2: Singleton pregnancy before 20th week of gestation, no risk for preterm delivery Control group: no pregnancy, no hormonal contraception Maximum of 20% smokers in each group

Exclusion criteria

Exclusion criteria: Study group 1 and 2: multiple pregnancy amniorrhoea menstruation like bleeding risk for endocarditis Study group 2: risk for preterm delivery Control group: Pregnancy, hormonal contraception

Design outcomes

Primary

Measure	Time frame
Raising of oral clinical parameters (Plaque-Index (PI), Gingiva-Index (GI) and Periodontal Screening Index (PSI) if PSI Code 3 and 4 periodontal status in addition) using a periodontal probe and visual as well as microbiological analyses with a molecular genetic test system and bacterial culture at time between 24th and 32nd week of gestation and maximal 4 weeks after delivery. Pregnant women without risk for preterm delivery will be emamined between 15th and 20th week of gestation in addition.	—

Measure

Time frame

Raising of oral clinical parameters (Plaque-Index (PI), Gingiva-Index (GI) and Periodontal Screening Index (PSI) if PSI Code 3 and 4 periodontal status in addition) using a periodontal probe and visual as well as microbiological analyses with a molecular genetic test system and bacterial culture at time between 24th and 32nd week of gestation and maximal 4 weeks after delivery. Pregnant women without risk for preterm delivery will be emamined between 15th and 20th week of gestation in addition.

—

Secondary

Measure	Time frame
Analyses and comparison of intraoral and vaginal microflora using bacterial culture of pregnant women with risk for preterm delivery between 24th and 32nd week of gestation.	—

Countries

Germany

Contacts

Public ContactJohan Wölber

Uniklinik Freiburg, Abteilung für Zahnerhaltungskunde und Parodontologie

johan.woelber@uniklinik-freiburg.de0761-27047310

Outcome results