2009 Novel Influenza A (H1N1)
Conditions
Interventions
Group 1: Among cases (acute respiratory infections or PCR-confirmed influenza) the following propotion will be assessed: Persons with and without vaccination against 2009 Novel Influenza A (H1N1)
Grou
Sponsors
Robert Koch-Institut, Abteilung für Infektionsepidemiologie
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: A resident of Berlin, a) who is hospitalized in one of the participating clinics of the Vivantes network, AND b) who is between 18 and 65 years old, AND c) who gave written informed consent to participate in the study, AND d) who is hospitalized due to an acute respiratory illness, defined as presence of the following symptoms in the past 10 days - at least one systemic symptom: fever, or chills, or musclepain, or headache, AND - at least one respiratory symptom: cough or sore throat OR - a suspected diagnosis of influenza, acute bronchitis, or pneumonia assessed by a medical doctor
Exclusion criteria
Exclusion criteria: Patients, a) who can not give written informed consent b) who have insufficient capability to communicate for medical reasons like aphasia or unconsciousness c) who live in a nursing home d) who have a history of severe anaphlaxis after vaccination e) who already had 14 days or earlier before hospitalization the diagnosis of 2009 Novel Influenza confirmed by PCR
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assessment of the effectiveness of pandemic influenza vaccines to prevent hospitalization due to acute respiratory illness or due to laboratory-confirmed infection with Novel Influenza A (H1N1) among adults between 18-65 years of age | — |
Secondary
| Measure | Time frame |
|---|---|
| Assessment and description of the disease burden of severe acute respiratory illness among adults between 18-65 years in Berlin on a weekly basis during the flu season 2009/10 || Description of clinical manifestations and complications among patients between 18-65 years of age, who are hospitalized due to 2009 Novel Influenza A (H1N1), and the identification of risk factors for severe disease | — |
Countries
Germany
Outcome results
None listed