I50
Conditions
Interventions
Group 1: Heart failure (HF) was treated following the recommended guidelines as documented in our standard operating procedures (www.charite.de/kardiologie)
Sponsors
Charité - Universitätsmedizin Berlin
Campus Virchow-Klinikum
Medizinische Klinik m.S. Kardiologie
Internistische Notaufnahme
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: -Acute congestive heart failure NYHA III-IV
Exclusion criteria
Exclusion criteria: - Acute ST-elevation myocardial infarction - Anemia (Hb < 10 g/dL) - Cardiac surgery within the last 4 weeks - Malignoma - Inability to give written informed consent - Age under 18 years
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cardiovascular Death and Re-admission to hospital for acute congestive heart failure, Assessment during telephone follow-up 1 year after index admission to the Emergency Department | — |
Secondary
| Measure | Time frame |
|---|---|
| Death of acute heart failure, Assessment during 1-year telephone follow-up. || Improvement of NYHA classification score, Evaluation by study physician during clinical assessment and questionning in telephone follow-up || Improvement of the patients physical ability. In order to evaluate the patient's physical constitution a 6-min walk test (6MWT) was performed according to Guyatt et al. Patients were asked to walk at a fast pace until exhaustion occurred or for a period of 6 min on a level surface 50 m in length. The total distance walked (in m) during the test was recorded. All tests were administered by one physician who was unaware of the MLHFQ and laboratory data. The 6-min walking test was assessed on the first day after admission, at day 2, 3, 5 and at discharge from the hospital. || Improvement of LV ejection fraction: Transthoracic echocardiography was performed within 24h after admission following international standards with respect to left ventricular function, diameters and valve function. The ejection fraction was determined using the Teichholz-formula on 5 consecutive heart cycles. In case of arrhythmias (predominately atrial fibrillation) ten cycles were analyzed. || Developing of BNP values during the course of standard heart failure therapy: For the BNP analysis, EDTA plasma was frozen at -20C° . BNP levels (in pg/ml) were measured at baseline and in inpatients at days 1, 2, 3 and 5 after admission as well as at discharge. || Score of the Self-assessment of patients quality of life: Minnesota Living with Heart Failure Questionnaire (MLHFQ): To assess quality of life, patients filled in a cross-cultural adaptation of the Minnesota Living with Heart Failure Questionnaire for German-speaking patients. The test ranged between 0 (no disability) and 100 (severe disability). The questionnaire was completed within 24 hours after admission. || Score of self-assessment health status with the SF-36: The SF-36 is currently the most widely used patient self asse | — |
Countries
Germany
Contacts
Public ContactJulia Searle
Charité Universitätsmedizin Berlin Campus Virchow Klinikum Med. Klinik m.S. Kardiologie Internistische Notaufnahme
Outcome results
None listed