glioblastoma C71.9
Conditions
Interventions
None listed
Sponsors
Universitätsklinikum
Rheinisch-Westfälische Technische Hochschule Aachen
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: new radiological diagnosis of a malignant glioma (MRT based) indication for surgical resection Karnofsky index of at least 70% no principal denial of chemotherapy no serious hematological, liver, kidney abnormalities precluding chemotherapy written informed consent of the patient
Exclusion criteria
Exclusion criteria: younger than 18 or older than 75 years preoperative a/o intraoperative verification of a pathology, incompatible with a malignant glioma (WHO grade III/IV) no histologically confirmed glioblastoma tumor infiltrates areas of the brain that preclude an adequate radiation dose prior tumor surgery or other treatment Karnofsky index of less than 70% severe cardiovascular disease severe hematological impairment, kidney a/o liver insufficiency which preclude chemotherapy stroke serious infection basic unwillingness to receive chemotherapy other malignancies (except basalioma) pregnancy or lactation women in childbearing age if contraception cannot be warranted dementia or other mental state which precludes comprehension of therapy and hence, informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| time to progression (TTP) | — |
Secondary
| Measure | Time frame |
|---|---|
| overall survival (OS) | — |
Countries
Belgium, Germany, Netherlands
Contacts
Public ContactFrank Oertel
Universitätsklinikum Rheinisch-Westfälische Technische Hochschule Aachen
Outcome results
None listed