Short-term psychotherapy for patients with panic disorder with or without agoraphobia - a randomised comparative study between the panic-focused psychodynamic and cognitive behavioural psychotherapy

Short-term psychotherapy for patients with panic disorder with or without agoraphobia - a randomised comparative study between the panic-focused psychodynamic and cognitive behavioural psychotherapy - PfPP

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00000245

Enrollment

Registered

2009-12-08

Start date

2006-01-27

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F41.0 F40.01

Interventions

Group 1: PfPP (panic-focused psychodynamic psychotherapy for patients with panic disorder) 25 sessions in three months Group 2: CBT (cognitive behavioral therapy) 25 sessions in three months

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Agoraphobia with Panic Disorder (F40.01) or Panic Disorder(F 41.0) Current symptoms (at least one panic attack within the last 4 weeks) Informed consent Sufficient command of the German language

Exclusion criteria

Exclusion criteria: Schizophrenia or affective psychosis. Current severe depression. Borderline personality disorder. Severe neurological or internal diseases. Substance addiction.

Design outcomes

Primary

Measure	Time frame
Principal outcome criterion is the reduction of panic-related symptoms at the follow-up 6-months after treatment. Panic-related symptoms are measured with standardized questionnaires and interviews, e. g. the AKV-MI/BSQ/ACQ questionnaires, the Hamilton Anxiety Scale, HAMA, and the Panic Disorder Severity scale, PDSS. To test the hypothized equivalence of both interventional arms adequate statistical procedures will be used. All questionnaires and interviews were conducted at all occasions of mneasurement.	—

Measure

Time frame

Principal outcome criterion is the reduction of panic-related symptoms at the follow-up 6-months after treatment. Panic-related symptoms are measured with standardized questionnaires and interviews, e. g. the AKV-MI/BSQ/ACQ questionnaires, the Hamilton Anxiety Scale, HAMA, and the Panic Disorder Severity scale, PDSS. To test the hypothized equivalence of both interventional arms adequate statistical procedures will be used. All questionnaires and interviews were conducted at all occasions of mneasurement.

—

Secondary

Measure	Time frame
Severity of the panic-related symptoms at the follow up 24-months after treatment. Security of Attachment (Adult Attachment Projective, Adult Attachment Scale), Levels of emotional Awareness (LEAS) and panic-specific reflective functioning (RF) are secondary targets of analyses. Furthermore additional questionnaires and interviews were conducted (e.g. STAI and SPAI for anxiety, BDI for depression, SCL-90 for general psychopathology, CDS for depersonalisation, IIP-D for interpersonal integration, GAF, BIKEP measuring satisfaction with therapy, and manual-adherence of all therapists). With the exception of the SCID and the BIKEPs all test and interviews were conducted at all occasions of measurement.	—

Measure

Time frame

Severity of the panic-related symptoms at the follow up 24-months after treatment. Security of Attachment (Adult Attachment Projective, Adult Attachment Scale), Levels of emotional Awareness (LEAS) and panic-specific reflective functioning (RF) are secondary targets of analyses. Furthermore additional questionnaires and interviews were conducted (e.g. STAI and SPAI for anxiety, BDI for depression, SCL-90 for general psychopathology, CDS for depersonalisation, IIP-D for interpersonal integration, GAF, BIKEP measuring satisfaction with therapy, and manual-adherence of all therapists). With the exception of the SCID and the BIKEPs all test and interviews were conducted at all occasions of measurement.

—

Countries

Germany

Contacts

Public ContactClaudia Subic-Wrana

Klinik und Poliklinik für Psychosomatische Medizin und Psychotherapie

claudia.subic-wrana@unimedizin-mainz.de06131172196

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 10, 2026