Regulation of microRNAs in progenitor cells of patients with coronary artery disease

Regulation of microRNAs in progenitor cells of patients with coronary artery disease - REMIRCAD-PC

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00000232

Enrollment

Registered

2009-10-14

Start date

2010-10-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I25

Interventions

None listed

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients with documented stable coronary artery disease. Written informed consent and willigness to give a sample of 20 ml venous blood.

Exclusion criteria

Exclusion criteria: - Active infection or fever - Pregnancy or breastfeeding - Chronic inflammatory disease (e.g. M. Crohn, Rheumatoid Arthritis) - HIV infection or active hepatitis - Neoplastic disease without documented complete remission within the past 5 years - Apoplectic insult within the past 3 months - Impaired renal function (creatinine >2.5 mg/dl) at the time of treatment - Relevant liver disease (GOT >2 ULN, or spontaneous INR >1.5) - Mental retardation - Any condition that per investigator?s judgment increases the patient?s risk or excludes adequate collection of study data - Participation in another clinical trial within the past 30 days

Design outcomes

Primary

Measure	Time frame
Detection of microRNAs in progenitor cells of patients with coronary artery disease and in healthy controls.	—

Countries

Germany

Contacts

Public ContactStefanie;Carmen Dimmeler;Urbich

Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Goethe-University Frankfurt;Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Goethe-University Frankfurt

dimmeler@em.uni-frankfurt.de;urbich@em.uni-franfurt.de+49-69-6301-7440;+49-69-6301-83985

Outcome results