Development and evaluation of diagnostic biomarker panels on the basis of microarray analysis for treatment planning of oral squamous cell carcinoma

Development and evaluation of diagnostic biomarker panels on the basis of microarray analysis for treatment planning of oral squamous cell carcinoma - Biomarker Panel

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00000199

Enrollment

Registered

2011-01-13

Start date

2009-04-15

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

oral squamous cell carcinoma

Interventions

Group 1: tissue sample

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: histologically diagnosed squamous cell carcinoma of the oral cavity, no adjuvant therapy

Exclusion criteria

Exclusion criteria: inoperability, tumour entities other than squamous cell carcinoma

Design outcomes

Primary

Measure	Time frame
The aim of our study is to develop a biomarker panel on the basis of gene expression anlysis by microarray technique. With the information of the altered gene expression of few selected marker genes a precise diagnosis, prognosis and individually adapted therapy regimen will be established. The requirement for this biomolecular diagnostic tool is to be reliable, cost-efficient, quick and sensitive. The microarray analysis of the collected samples is carried out at the moment with special softwear and not finished yet.	—

Measure

Time frame

The aim of our study is to develop a biomarker panel on the basis of gene expression anlysis by microarray technique. With the information of the altered gene expression of few selected marker genes a precise diagnosis, prognosis and individually adapted therapy regimen will be established. The requirement for this biomolecular diagnostic tool is to be reliable, cost-efficient, quick and sensitive. The microarray analysis of the collected samples is carried out at the moment with special softwear and not finished yet.

—

Secondary

Measure	Time frame
One aim of our project was to develop a simple and economic device to diagnose and categorize the oral squamous cell carcinoma on the basis of clinical data combined with genetic alterations.	—

Countries

Germany

Contacts

Public ContactJohannes Kleinheinz

Klinik für Mund-, Kiefer- und Gesichtschirurgie

Johannes.Kleinheinz@ukmuenster.de00492518347001

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026