healthy adults with vitamin D deficiency E56.9
Conditions
Interventions
Group 1: verum group: the probands get a defined amount of Vitamin D (350µg) in form of a Vitamin D fortified (by UVB radiation) mushroom soup every week over a period of 4 weeks.
Group 2: active cont
Sponsors
Medizinische Universitätsklinik Freiburg - Abteilung Innere Medizin I
Hämatologie und Onkologie
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: - healthy general condition based on medical history and examination at admission - body mass index (BMI) between 18,5 and 26 kg/m² - serum 25(OH)D < 25 ng/ml (< 50 nM) - serum calcium in normal range 2,15 ? 2,55 mM - written informed consent of the participants after educational advertising
Exclusion criteria
Exclusion criteria: - anamnesis of kidney stone - pregnancy - white button mushrooms intolerance or allergy - visit of a tanning salon right before or during the study - eating fish or liver during the study - taking supplements of Vitamin D during the study - abidance in the mountains or southern countries during the study - serum calcium > 5,2 mM during the study - cancellation of the informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Significant rising of the serum 25(OH)D level from young healthy adults by the consumption of UV-B treated mushrooms compared to non-treated mushrooms. Serum 25(OH)D level will be measured 4 times on each weekly encounter and 1 time a week after the last soup administration. | — |
Secondary
| Measure | Time frame |
|---|---|
| Equality of UV-B treated mushrooms compared to a normal Vitamin D2 supplement in regard to improve the 25(OH)D status. The 25(OH)D status will be measured at the five weekly encounters. | — |
Countries
Germany
Contacts
Public ContactPaul Urbain
Uniklinik Freiburg - Medizinische Klinik I Sektion Ernährungsmedizin & Diätetik
Outcome results
None listed