LigaSure Impact TM versus conventional dissection in pylorus-preserving pancreatoduodenectomy (pp-Whipple) at suspicion of pancreatic head cancer

LigaSure Impact TM versus conventional dissection in pylorus-preserving pancreatoduodenectomy (pp-Whipple) at suspicion of pancreatic head cancer - DISSECT-Studie

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00000166

Enrollment

100

Registered

2009-08-28

Start date

2009-10-15

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C25.0 C24.1 C24.0 C17.0

Interventions

Group 1: Control group: conventional dissection with conventional hemostasis (e.g. ligature, suture, clip) Group 2: Experimental group: Dissection with LigaSure

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Older than 18years; clinical suspect for pancreatic head cancer, papilla, distal bile-duct or duodenal carcinoma; operative indication for standard pp-Whipple; written consensus.

Exclusion criteria

Exclusion criteria: Patients that take place in other clinical studies. Restricted mental status and language difficulties.

Design outcomes

Primary

Measure	Time frame
Operating time (cut/sutural time)	—

Secondary

Measure	Time frame
1. Mortality 2. Intra- and postoperative complications 3. Intraoperative blood loss 4. Hospital stay 5. Hospital re-entry rate (30 days postoperative) 6. Induction and reversal time of anesthesia (anesthesia and operation log) 7. Material consumption perioperative 8. Material costs of the operation 9. Overall costs of the operation 10. Local recrudescence (standard follow-up care) 11. Quality of life (quality of life questionary)	—

Measure

Time frame

1. Mortality 2. Intra- and postoperative complications 3. Intraoperative blood loss 4. Hospital stay 5. Hospital re-entry rate (30 days postoperative) 6. Induction and reversal time of anesthesia (anesthesia and operation log) 7. Material consumption perioperative 8. Material costs of the operation 9. Overall costs of the operation 10. Local recrudescence (standard follow-up care) 11. Quality of life (quality of life questionary)

—

Countries

Germany

Contacts

Public ContactDagmar Anders

Klinisches Studienzentrum der Chirurgie (KSC)

Dagmar.Anders@med.uni-heidelberg.de06221 /5636459

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 28, 2026