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Effectiveness of periodontal therapy in HIV-seropositive patients with chronic periodontitis undergoing highly-active antiretroviral therapy

Effectiveness of periodontal therapy in HIV-seropositive patients with chronic periodontitis undergoing highly-active antiretroviral therapy - HIV-cP6 study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00000097
Enrollment
32
Registered
2009-07-28
Start date
2012-05-15
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

K05.3

Interventions

Group 1: Arm 1: Test group patients with HIV infection Scaling / Root planing in 2003, till 2009 supportive periodontal therapy post intervention control: clinical parameter of attachment, marginal

Sponsors

Universität Witten/Herdecke Geschäftführung Wissenschaftliche Direktion
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: -Systematic periodontla therapy in 2003 -HIV-seropositive status (only test group) -Antiretroviral therapy with immunoreconstitution (only test group) -Informed consent

Exclusion criteria

Exclusion criteria: -Additional systemic diseases associated with periodontal disease (e.g. diabetes mellitus) -Intake of drugs, that may lead to gingival hyperplasia (e.g. anticonvulsants) -No informed consent

Design outcomes

Primary

MeasureTime frame
Target variable: Retention of teeth Parameter: tooth in situ Scheduled: 5 yrs postoperative Methode: clinical oral examination Instrument: eye, x-ray

Secondary

MeasureTime frame
Target parameter I: Microbial load Parameter: Periodontal pathogens Schedule: 5 yrs postoperative Method: DNA-Chip Instrument: ParoCheck10 Target parameter II: Attachment level Parameter: Pocket probing depth and recession Schedule: 5 yrs postoperative Method: clinical examination Instrument: WHO periodontal probe Target parameter III: Marginal inflammation Parameter: Bleeding on probing of the marginal gingiva Schedule: 5 yrs postoperative Method: Bleeding on probing Instrument: WHO periodontal probe

Countries

Germany

Contacts

Public ContactA. Rainer Jordan

Universität Witten/Herdecke Fakultät für Gesundheit i. G. Department für Zahn-, Mund- und Kieferheilkunde Abteilung für Zahnärztliche Propädeutik

andreas.jordan@uni-wh.de+49 (2302) 926-607

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026