Diseases of the circulation system I20-I25
Conditions
Interventions
Group 1: Evaluation of myocardial velocities in patients with LVEDD>55 mm:
Patients with dilatative cardiomyopathy
Group 2: Evaluation of myocardial velocities in patients with LVEDD>55 mm:
Patients w
Sponsors
Universitätsklinikum Freiburg
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Part 1: Patients with LVEDD>55 mm: 20 patients with dilatative cardiomyopathy 20 patients with relevant mitral- oder aortic insufficiency 20 patients with arterial hypertension or aortic stenosis Part 2: 20 patients with suspected CAD Part 3: 20 patients with acute myocardial infarction Amendment: 1. 60 additional healthy volunteers 2. 20 patients with complete left bundle branch block without cardiac disease and normal LVEF 3. 50 patients mit with complete left bundle branch block, LVEF=35%, LVEDD > 55 mm and heart failure (NYHA class = II) with dilated cardiomyopathy before CRT 4. 80 patients after heart transplantation (also follow-up)
Exclusion criteria
Exclusion criteria: Part 1: CAD, contraindications against MRI Part 2: Contraindications against MRI, Gadolinium or Adenosin. Reduced left ventricular function, relevant valvular disease, left bundle branch block. Part 3: Contraindications against MRI, Gadolinium or Adenosin. Reduced left ventricular function, relevant valvular disease, left bundle branch block.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Differences/changes of myocardial motion | — |
Secondary
| Measure | Time frame |
|---|---|
| in patients after HTX or CRT: changes of clinical parameters (NYHA classes etc.) | — |
Countries
Germany
Contacts
Public ContactDaniela Föll
Kardiologie und Angiologie I, Universitäts Herzzentrum freiburg
Outcome results
None listed