Mild decline in sleep quality and declined skin physiological function
Conditions
Interventions
Test product Group 2:Ergothioneine Capsules (60 mg)
Test Article Group 1:Ergothioneine Capsules (20 mg)
Sponsors
The First People's Hospital of Kunshan
Eligibility
Sex/Gender
All
Age
20 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1. Healthy adults aged 20 to 55 years inclusive, of all genders; 2. Self-perceived sleep disturbance or deteriorated skin condition; 3. They fully understand the research objectives and trial procedures and voluntarily sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Receiving ongoing treatment for sleep disorders; 2. Pittsburgh Sleep Quality Index (PSQI) score > 8, or Skin Quality Scale (SQS) score >= 19; 3. Engaged in night-shift work and planning to alter regular sleep schedules; 4. Routine intake of antioxidant medicines, health foods and nutritional supplements (such as VC, VE, tea polyphenols, etc.); 5. Daily mushroom intake > 100 grams per day; 6. Average habitual alcohol intake > 60 grams per day within the past 3 months; 7. Patients suffering from severe cardiovascular, endocrine or urinary system diseases; 8. Being pregnant or breastfeeding at present or planning to become pregnant during the trial; 9. Those with known allergies to any ingredient of the test product; 10. Those participating in or planning to join other clinical trials; 11. Other conditions where the investigator judges poor compliance or unsuitability for participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pittsburgh Sleep Quality Index (PSQI) score;Skin physicochemical indicators (skin firmness and elasticity); | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse Events (AEs) and Serious Adverse Events (SAEs);Objective monitoring by sleep-tracking wristband;Serum hormone levels (cortisol, melatonin);Skin Quality Scale (SQS) score;Oxidative stress indicators (SOD, MDA, GSH);Inflammatory factors (IL-6, TNF-a);Skin physicochemical indicators;Dietary Questionnaire; | — |
Countries
China
Contacts
Public ContactChen Yafang
The First People's Hospital of Kunshan
Outcome results
None listed