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Application of Multimodal Radiomics in Differentiation of Benign and Malignant Soft Tissue Tumors and Assessment of Tumor Microenvironment

Application of Multimodal Radiomics in Differentiation of Benign and Malignant Soft Tissue Tumors and Assessment of Tumor Microenvironment

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600132245
Enrollment
Unknown
Registered
2026-09-11
Start date
2025-10-04
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Soft tissue tumors

Interventions

Benign tumor group:None

Sponsors

The second hospital of Dalian Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Patients clinically diagnosed with soft tissue tumors of the extremities and trunk without any prior anti-tumor treatment before imaging examination. 2.Tumor volume>1 cm³. 3.All patients were fully informed, provided written informed consent and agreed to participate in this study. 4.Patients who underwent surgical resection with definitive pathological diagnosis obtained.

Exclusion criteria

Exclusion criteria: 1.Patients with lesions definitively diagnosed as epidermal cyst, ganglion cyst, hematoma or abscess by ultrasonography. 2.Patients with excessively large masses that cannot be fully displayed on ultrasound. 3.Patients with contraindications to DCE-MRI such as implanted metallic foreign bodies, or those unable to complete MRI examination due to poor compliance. 4.Patients whose ultrasound or MRI image quality fails to meet the research requirements.

Design outcomes

Primary

MeasureTime frame
Shear Wave Velocity;Vascular Index;Dynamic Contrast-Enhanced Magnetic Resonance Imaging;

Secondary

MeasureTime frame
Ki-67;Diagnostic performance: area under the curve (AUC), accuracy, precision, recall, F1-score;

Countries

China

Contacts

Public ContactWu Jun

The second hospital of Dalian Medical University

wujun108@sina.com+86 17709873905

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Sep 19, 2026