Postoperative Fatigue Syndrome
Conditions
Interventions
sham-taVNS group:sham-Transcutaneous auricular vagus nerve stimulation
Sponsors
Huzhou Center Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. age >=18 years; 2. scheduled for elective hysterectomy; 3. American Society of Anesthesiologists (ASA) physical status I–III; 4. preoperative Christensen Fatigue Scale score <=4; 5. no history of local skin disease affecting the left auricular concha; 6. voluntary provision of written informed consent; 7. no participation in any other clinical trial within the past 3 months;
Exclusion criteria
Exclusion criteria: 1.cognitive dysfunction; 2.severe cardiovascular disease (congestive heart failure, myocardial infarction within the past 6 months, grade III hypertension, severe arrhythmias, stroke with sequelae); 3.hepatic/renal insufficiency (Child-Pugh class C / CKD stage G4); 4.active asthma or acute exacerbation of chronic obstructive pulmonary disease; 5.sinus bradycardia (heart rate <50 beats/min); 6.tinnitus or hoarseness; 7.history of recurrent vasovagal syncope; 8.history of vagotomy;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of postoperative fatigue syndrome; | — |
Secondary
| Measure | Time frame |
|---|---|
| postoperative recovery;Adverse Event;pain;Handgrip strength;Hospital Anxiety and Depression Scale;ICFS-10 scale (10 to 50 points) score;Exploratory follow-up indicators;Richards-Campbell Sleep Questionnaire (RCSQ);Markers of systemic inflammation; | — |
Countries
China
Contacts
Public ContactKeyu Fan
Huzhou Center Hospital
Outcome results
None listed