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Development and Validation of a Nomogram for Pre-Biopsy Prediction of Breast Cancer in Patients with Nipple Discharge

Development and Validation of a Nomogram for Pre-Biopsy Prediction of Breast Cancer in Patients with Nipple Discharge

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600131804
Enrollment
Unknown
Registered
2026-09-07
Start date
2025-09-01
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nipple discharge

Interventions

Sponsors

Jiangsu Province Hospital (The First Affiliated Hospital with Nanjing Medical University)
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1.Patients admitted to the Breast Center of Jiangsu Province Hospital from January 2013 to December 2020 who presented with nipple discharge as the initial symptom and underwent surgical treatment. 2.The age of onset ranged from 18 to 90 years old. 3.They completed preoperative examinations and surgical treatment at Jiangsu Province Hospital, with complete data including preoperative physical examinations, imaging examinations and postoperative paraffin pathology.

Exclusion criteria

Exclusion criteria: 1.Patients with physiological nipple discharge or drug-induced nipple discharge. 2.Patients with other malignant tumors or a previous history of breast cancer. 3.Women who were pregnant or lactating.

Design outcomes

Primary

MeasureTime frame
Postoperative routine pathological findings;

Secondary

MeasureTime frame
Age, marital history, menstrual history, pregnancy history, delivery history, breastfeeding history, hypertension history, diabetes history,etc.;

Countries

China

Contacts

Public ContactWang Jue

Jiangsu Province Hospital (The First Affiliated Hospital with Nanjing Medical University)

wangjue200011@163.com+86 18061695508

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Sep 19, 2026