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Analysis of Corneal Epithelial Thickness Distribution Characteristics and Their Influencing Factors in Myopic Patients

Analysis of Corneal Epithelial Thickness Distribution Characteristics and Their Influencing Factors in Myopic Patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600131611
Enrollment
Unknown
Registered
2026-09-04
Start date
2026-09-10
Completion date
Unknown
Last updated
2026-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myopia

Interventions

Sponsors

Shenzhen People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18–45 years. 2. Meeting the diagnostic criteria for myopia (SE <= -0.50 D). 3. Classified as having low, moderate, or high myopia according to SE. 4. Stable refractive status, defined as a change of <=0.50 D within the past year. 5. Absolute value of astigmatism (cylinder) <=1.50 D. 6. Binocular anisometropia <1.50 D, calculated as the interocular difference in spherical equivalent. 7. Scheduled to undergo corneal refractive surgery and having completed a full preoperative examination. 8. Able to cooperate with corneal epithelial thickness measurement and related examinations. 9. Transparent cornea without obvious structural abnormalities. 10. Voluntarily participating in this study and having signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1.Keratoconus or suspected keratoconus; 1.suspected keratoconus will be determined based on corneal topography or corneal tomography findings; 2.Previous history of corneal refractive surgery or other ocular surgery; 3.Active ocular surface disease, such as obvious dry eye, keratitis, conjunctivitis, etc. 4.Corneal scar, corneal dystrophy, or other corneal abnormalities; 5.Recent contact lens wear, defined as soft contact lens wear within 2 weeks or rigid contact lens/orthokeratology lens wear within 4 weeks; 6.Ocular diseases affecting corneal status, such as glaucoma or uveitis; 7.Systemic diseases that may affect corneal structure, such as diabetes mellitus or autoimmune diseases; 8.Poor-quality OCT images or incomplete data.

Design outcomes

Primary

MeasureTime frame
Corneal epithelial thickness within the 9-mm zone;

Secondary

MeasureTime frame
Directional differences in corneal epithelial thickness;

Countries

China

Contacts

Public ContactNie Aiqin

Shenzhen People's Hospital

261376044@qq.com+86 755 2553 3018

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Sep 19, 2026