Skip to content

The Effects of High-Frequency Electrotherapy Combined with Infrared Irradiation on Pain and Local Microcirculation in Patients with Subacute Knee Ligament Injuries

The Effects of High-Frequency Electrotherapy Combined with Infrared Irradiation on Pain and Local Microcirculation in Patients with Subacute Knee Ligament Injuries

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600131545
Enrollment
Unknown
Registered
2026-09-03
Start date
2026-10-01
Completion date
Unknown
Last updated
2026-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee ligament injury

Interventions

Experimental group:Standard rehabilitation exercises, high-frequency therapy combined with infrared treatment

Sponsors

The First People’s Hospital of Lianyungang
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: (1) Meets the diagnostic criteria for subacute ligament injury of the knee joint (medial collateral ligament, lateral collateral ligament, cruciate ligament), with injury duration of 2-6 weeks, confirmed by physical examination (ligament stress test, etc.) and imaging examination (ultrasound or MRI). MRI accuracy for grading soft tissue injuries can reach over 92%, allowing clear determination of injury severity and exclusion of complete ligament rupture; (2) Aged 18-60 years, regardless of gender. Patients in this age group generally have good limb function, high compliance with treatment, and exclusion of the impacts of immature skeletal development in adolescents and functional decline in the elderly on treatment outcomes; (3) Clear injury location, accompanied by local pain and swelling, limited knee joint activity, VAS pain score >= 4 points (moderate pain), consistent with subacute phase pain and functional impairment characteristics, ensuring that study subjects have clear treatment needs and observational value, while excluding patients with mild pain who do not require intensified analgesic intervention; (4) Voluntary participation in this study, able to understand the study procedures, cooperate with treatment, efficacy evaluation, and follow-up, and sign a written informed consent form; (5) No contraindications to high-frequency or infrared therapy (such as skin infection, breakdown, allergy, or pacemaker implantation), ensuring treatment safety.

Exclusion criteria

Exclusion criteria: (1) Patients with complete knee ligament rupture requiring surgical treatment: such patients need surgical intervention, and physical therapy is only auxiliary, which does not meet the research objective of non-drug interventions; (2) Patients with concomitant knee fractures, dislocations, meniscus injuries, cartilage injuries, or neurovascular injuries: these patients have complex conditions that affect efficacy evaluation and may require other targeted treatments, interfering with the assessment of the research treatment program's effectiveness; (3) Patients with severe cardiovascular and cerebrovascular diseases, liver and kidney dysfunction, coagulation disorders, or diabetes (poorly controlled blood glucose), or other systemic diseases: such conditions may affect local tissue repair and microcirculation, and may increase the risk of adverse reactions to treatment; (4) Patients with skin damage, infections, eczema, allergic constitution, or allergies to infrared, high-frequency treatment, or topical medications: to avoid adverse skin reactions during treatment and ensure treatment safety; (5) Pregnant or breastfeeding women: to avoid potential effects of high-frequency and infrared treatments on the fetus or infant; (6) Patients who have recently (within 1 month) received other pain relief treatments, physiotherapy (such as acupuncture, massage, shock wave therapy, etc.) or related drug treatments: such treatments may affect the evaluation of the efficacy in this study; (7) Patients with mental illness, cognitive impairment, or intellectual disability who cannot cooperate with treatment, efficacy assessment, or follow-up; (8) Patients who are difficult to follow up and are expected to be unable to complete the full course of treatment and observation follow-up, to avoid excessive dropout cases affecting the reliability of the study results.

Design outcomes

Primary

MeasureTime frame
VAS Pain Score;Local microcirculatory blood flow;

Secondary

MeasureTime frame
Degree of knee swelling;Range of motion of the knee joint;Local skin temperature of the knee joint;

Countries

China

Contacts

Public ContactLu Yu

The First People’s Hospital of Lianyungang

18961321365@189.com+86 189 6132 1365

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Sep 19, 2026