Cervical cancer
Conditions
Interventions
PBMS Group:Pelvic Bone Marrow Sparing Radiotherapy
Sponsors
The First Affiliated Hospital of China Medical University
Eligibility
Sex/Gender
Female
Age
20 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Confirmed by pathological gynecologic examination as cervical cancer; 2. Inclusion of patients with stage Ib2-IIIb cervical cancer without prior radiation or chemotherapy (staging according to the 2018 NCCN guidelines FIGO staging); 3. Patient age >= 20 years and <= 80 years; 4. Patient voluntarily participates and signs an informed consent form, has good compliance, and can cooperate with the study according to the protocol requirements.
Exclusion criteria
Exclusion criteria: 1. Cases requiring abdominal extended-field irradiation. 2. History of prior bone-related diseases (e.g., femoral head necrosis) or muscle-related diseases, or prior hip joint implantation or femoral head replacement. 3. History of prior bisphosphonate therapy, hormone replacement therapy, or similar treatments. 4. History of occupational exposure factors (e.g., paint, decoration, nail art industries) and blood-related diseases. 5. History of prior pelvic irradiation. 6. Planned participation in other clinical studies. 7. Other conditions judged by the investigator that may affect the conduct of the clinical study or the interpretation of the study results. 8. Refusal or inability to sign the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Local Control Rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hematotoxicity;Intestinal injury;Urinary system injury;Skeletal injury; | — |
Countries
China
Contacts
Public ContactLi Guang
The First Affiliated Hospital of China Medical University
Outcome results
None listed