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Development and Validation of a Clinical Prediction Model for Difficult Laryngoscopy in Children With Microtia

Development and Validation of a Clinical Prediction Model for Difficult Laryngoscopy in Children With Microtia Based on Preoperative Conventional Airway Assessment Indicators

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600131244
Enrollment
Unknown
Registered
2026-08-31
Start date
2026-09-15
Completion date
Unknown
Last updated
2026-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Microtia

Interventions

Prospective validation cohort:None
Retrospective development cohort:None

Sponsors

Plastic Surgery Hospital, Chinese Academy of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
5 Years to 12 Years

Inclusion criteria

Inclusion criteria: 1.Children aged 5–12 years; 2.Diagnosed with congenital microtia; 3.Scheduled for elective surgery requiring general anesthesia with endotracheal intubation; 4.Undergoing initial glottic exposure assessment using direct laryngoscopy after induction of general anesthesia; 5.Written informed consent provided by a parent or legal guardian for participation in the prospective study component.

Exclusion criteria

Exclusion criteria: 1.History of cervical spine trauma, cervical spine surgery, or severe cervical spine disorders resulting in significant limitation of neck mobility; 2.Presence of congenital syndromes known to independently cause severe craniofacial and airway abnormalities, including Treacher Collins syndrome, Pierre Robin sequence, Apert syndrome, and Crouzon syndrome; 3.Absence of documented Cormack–Lehane laryngoscopic grading; 4.Severe missingness of key predictor variables precluding model development or validation; 5.Refusal to participate in the prospective study or failure of a parent or legal guardian to provide written informed consent (prospective cohort only).

Design outcomes

Primary

MeasureTime frame
Difficult Laryngoscopy;Model performance evaluation (discrimination, clinical practicability);—

Secondary

MeasureTime frame
Sex;Body weight;Upper lip bite test;Inter-incisor distance;Body mass index;Neck circumference;Hemifacial microsomia;Sternomental distance;Predictive performance of the clinical prediction model for difficult laryngoscopy;Age;Modified Mallampati classification;Thyromental distance;Height;Laterality of microtia;Prospective cohort intraoperative conditions (intubation method; laryngoscope exposure classification; whether alternative airway tools are needed; airway complications (laryngeal spasm, decreased oxygen saturation, etc.));—

Countries

China

Contacts

Public ContactLiu Quayle

Plastic Surgery Hospital, Chinese Academy of Medical Sciences

491293701@qq.com+86 10 53968479

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Sep 19, 2026