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Study on the correlation between the degree of lens zonular laxity and the ultrastructure of lens capsule and ocular biological parameters in patients with primary angle closure disease

Study on the correlation between the degree of lens zonular laxity and the ultrastructure of lens capsule and ocular biological parameters in patients with primary angle closure disease

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600130763
Enrollment
Unknown
Registered
2026-08-24
Start date
2026-09-01
Completion date
Unknown
Last updated
2026-08-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary angle closure disease

Interventions

Group with Suspected Primary Anterior Chamber Angle Closure:None
Primary Atrial Angle Closure Group:None
Simple Age-Related Cataract:None

Sponsors

Peking University Third Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients diagnosed with primary angle-closure glaucoma and concomitant lens subluxation cataract; 2. Aged 45 to 75; 3. The eyes included in the study had stable intraocular pressure (IOP) within 20 mmHg, either through peripheral iridectomy with laser drilling, trabeculectomy, anti-glaucoma medication, or no treatment; 4. Routine preoperative biological measurements can be completed for patients who are scheduled to undergo cataract surgery

Exclusion criteria

Exclusion criteria: 1. Eye diseases affecting the stability of the lens zonules, such as ocular trauma history and exfoliation syndrome; 2. Neovascular glaucoma, secondary glaucoma due to uveitis, and secondary angle-closure glaucoma; 3. Previous history of intraocular surgery; 4. The opposite eye is in an artificial lens implantation state; 5. The opposite eye exhibits significant lens subluxation

Design outcomes

Primary

MeasureTime frame
preoperative ocular biological examinations;

Secondary

MeasureTime frame
electron microscopy examination for anterior capsule;

Countries

China

Contacts

Public ContactXu Ke

Peking University Third Hospital

doctorxuke@163.com+86 82266319

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Sep 19, 2026