Anxiety Comorbid with Disorders of Gut-Brain Interaction
Conditions
Interventions
No rTMS group:None
Sponsors
The 8th Medical Center of PLA General
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Confirmed to meet the ICD-10 anxiety disorder and Rome V diagnostic criteria; 2. Currently receiving SSRI drug treatment (>=2 weeks, stable dose); 3. Aged 18 to 75 years, gender not limited, signed informed consent; 4. No history of organic diseases of the lungs, liver, kidneys and brain.
Exclusion criteria
Exclusion criteria: 1. Secondary constipation, such as intestinal tumors, intestinal obstruction, hypothyroidism and other organic diseases; 2. Contraindications for rTMS treatment (such as having metal implants in the body, history of epilepsy); 3. Allergy to anti-anxiety or constipation drugs used in the study; 4. Participation in other clinical studies within the last 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change from baseline in FDDQL score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Change from baseline in Symptom Checklist-90 (SCL-90) score;heart rate variability; | — |
Countries
China
Contacts
Public ContactZhang Lin
The 8th Medical Center of PLA General
Outcome results
None listed