Postoperative anxiety, depression, and mood disturbance in patients with functional pituitary adenomas
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients aged 18–70 years, regardless of sex; 2.Diagnosed with a functioning pituitary adenoma based on clinical manifestations, endocrine evaluation, and contrast-enhanced pituitary MRI, and scheduled to undergo first-time elective transsphenoidal pituitary tumor resection; 3.Conscious and able to understand the study procedures and complete the required questionnaires.
Exclusion criteria
Exclusion criteria: 1.A documented history of psychiatric disorders, or regular use of antidepressants, anxiolytics, or antipsychotic medications within the preceding 3 months; 2.Presence of other intracranial tumors or severe cardiac, pulmonary, hepatic, or renal dysfunction; 3.Presence of an evident risk of self-harm or suicide, or a need for urgent psychiatric or psychological intervention; 4.Pregnancy or lactation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SAS score at postoperative day 7 and change from baseline; | — |
Secondary
| Measure | Time frame |
|---|---|
| SDS score at postoperative day 7 and change from baseline;NOSIE-30 score at postoperative day 7;Patient care satisfaction;length of hospital stay; | — |
Countries
China
Contacts
Qilu Hospital of Shandong University