Overweight and Obesity
Conditions
Interventions
Sponsors
Peking Union Medical College Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Age >=18 years; 2.BMI>=24 kg/m^², indicating overweight or obesity; 3.Availability of complete baseline and follow-up clinical data, including routine laboratory test results such as body weight, serum uric acid, and blood glucose; 4.Outpatient visits at Peking Union Medical College Hospital, with a follow-up duration of >=6 months.
Exclusion criteria
Exclusion criteria: 1.Estimated glomerular filtration rate (eGFR) <30 mL/min/1.73 m^²; 2.Initiation of urate-lowering medications during follow-up, including allopurinol, febuxostat, benzbromarone, etc. 3.Severely incomplete clinical data precluding assessment of the primary study outcomes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum uric acid; | — |
Secondary
| Measure | Time frame |
|---|---|
| Body weight and body composition indicators: body weight, BMI, body fat percentage, and visceral fat area;Lipid profile, including TC, TG, HDL-C, and LDL-C;Glucose metabolism indicators: fasting blood glucose, fasting insulin, HbA1c, and HOMA-IR;Clinical characteristics, comorbidities, and medication use: age, sex, comorbidities, and medication use;Renal function and inflammatory indicators: serum creatinine, eGFR, and hsCRP; | — |
Countries
China
Contacts
Public ContactZhu Huijuan
Peking Union Medical College Hospital
Outcome results
None listed