Ischemic stroke, hemorrhagic stroke, post-stroke neurological deficit, limb motor dysfunction
Conditions
Interventions
Normal control group:None
Sponsors
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
45 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Stroke patients meet the diagnostic criteria of Chinese Classification of Cerebrovascular Diseases 2019, confirmed as ischemic or hemorrhagic stroke by cranial CT/MRI; healthy volunteers have no cerebrovascular or neurological underlying diseases. 2.Aged 45–80 years old, male and female are eligible. 3.MoCA score ranges from 10 to 26 with acceptable cognition, no severe visual or auditory impairment and fluent communication. 4.Stable vital signs and capable of completing resting and motor-task EEG acquisition. 5.All subjects are fully informed and voluntarily sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Traumatic intracranial hemorrhage or subarachnoid hemorrhage; 2. Combined with other neurological diseases (such as epilepsy, Parkinson's disease, etc.); 3. Severe cardiopulmonary insufficiency (NYHA cardiac function class III-IV); 4. Implanted cardiac pacemaker or defibrillator; 5. Scalp infection or skull defect interfering with EEG acquisition; 6. Prior history of psychiatric disorders (DSM-V diagnosis); 7. Severe hepatic and renal dysfunction (eGFR 3 times the upper limit of normal); 8. Concurrent participation in other interventional clinical trials; 9. Female subjects during pregnancy or lactation; 10. Persistent electrode impedance > 10 kO with no improvement after 3 adjustments; 11. Emergent medical events occurring during data acquisition (e.g., epileptic seizure); 12. Missing rate of key data > 30% (e.g., EEG signal interruption longer than 5 minutes); 13. Motion artifact score (MAQS) >= 4, independently assessed by 3 technicians; 14. Final diagnosis inconsistent with stroke criteria (confirmed by cranial MRI/CT); 15. Incomplete clinical data (lack of imaging report obtained within 24 hours after onset);
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Accuracy of stroke subtype identification; | — |
Secondary
| Measure | Time frame |
|---|---|
| Baseline cerebral functional assessment;Motor cortex activation evaluation; | — |
Countries
China
Contacts
Public ContactJiang Xiaobing
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed