Stroke (including ischemic stroke and hemorrhagic stroke)
Conditions
Interventions
Sponsors
Xuzhou Rehabilitation Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1.Diagnosed with acute ischemic stroke according to the Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke 2023 or with intracerebral hemorrhage according to the Chinese Guidelines for the Diagnosis and Treatment of Intracerebral Hemorrhage 2023, confirmed by cranial CT or MRI; 2.First-ever stroke or no significant residual neurological deficits from prior stroke (modified Rankin Scale [mRS] score = 1); 3.Admitted within 14 days of stroke onset; 4.Aged 40–85 years; 5.Written informed consent provided by the patient or their legal guardian; 6.Able to cooperate with cognitive assessment and follow-up;
Exclusion criteria
Exclusion criteria: 1.Pre-existing cognitive impairment (Mini-Mental State Examination [MMSE] score < 27) or a clear history of dementia prior to stroke onset; 2.Concurrent severe organ failure involving the heart, liver, or kidneys (e.g., New York Heart Association [NYHA] functional class III–IV, end-stage renal disease, etc.); 3.Concurrent psychiatric disorders such as schizophrenia or major depressive disorder, or presence of aphasia, visual or hearing impairment that prevents completion of cognitive assessment; 4.Life expectancy < 1 year; 5.Currently participating in other clinical trials that may affect the outcomes of this study; 6.History of alcohol or drug dependence;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montreal cognitive assessment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Functional Comprehensive Assessment cognitive domain total score;Prediction model performance metrics;Age; sex; years of education; stroke type; admission NIHSS score; lesion location; hypertension; diabetes mellitus; atrial fibrillation; dyslipidemia; previous stroke history; smoking history; alcohol consumption history; white matter hyperintensities; brain atrophy; homocysteine; high-sensitivity C-reactive protein; | — |
Countries
China
Contacts
Public ContactMa Zhezhe
Xuzhou Rehabilitation Hospital
Outcome results
None listed