Healthy Chinese adults
Conditions
Interventions
Sponsors
Tianjin Medical University Eye Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age >= 18 years, with no restriction on sex; 2.Best corrected visual acuity (BCVA) >= 0.5, normal intraocular pressure, and no active ocular diseases that may affect pupillary function or measurement results (such as glaucoma or iridocyclitis) detected by slit-lamp examination; 3.No history of systemic diseases that may affect autonomic nervous function or pupillary reflexes, such as diabetes mellitus, Parkinson’s disease, or Horner syndrome; 4.No recent use of medications (such as mydriatic agents, miotic agents, antidepressants, or antihistamines), cosmetics, or health supplements that may influence pupil size or dynamic pupillary responses; 5.Participants are able to understand and comply with all study procedures and voluntarily provide written informed consent;
Exclusion criteria
Exclusion criteria: 1.History of ocular surgery or significant ocular trauma, or presence of organic ocular diseases that may affect pupillary function, including glaucoma, uveitis, iris disorders, mature cataract, severe corneal diseases, or optic nerve diseases; 2.Neurological disorders that may affect pupillary reflexes, including Horner syndrome, oculomotor nerve palsy, Parkinson’s disease, and multiple sclerosis; 3.Systemic diseases associated with significant autonomic neuropathy; 4.Use of medications, cosmetics, or health supplements that may affect pupillary function within 1 week before the examination, including atropine, pilocarpine, antihistamines, antidepressants, sedative-hypnotic agents, and other related agents; 5.Other conditions considered inappropriate for participation by the investigators;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dynamic pupil parameters: constriction latency, constriction amplitude, constriction duration, average constriction velocity, dilation duration, and average dilation velocity;Static pupil parameters: scotopic pupil diameter (SPD), mesopic pupil diameter (MPD), and photopic pupil diameter (PPD); | — |
Countries
China
Contacts
Public ContactZhiqing Li
Tianjin Medical University Eye Hospital
Outcome results
None listed