Acute kidney failure
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Meet the KDIGO 2012 diagnostic criteria for acute kidney injury (AKI). 2.Have clinical indications for renal biopsy and require pathological examination to clarify the etiology; 3.Age >=18 years, any gender, and voluntarily sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Presence of contraindications to renal biopsy (e.g., severe coagulation disorders, uncontrolled hypertension, solitary kidney, renal malformation or tumor, active infection). 2.End-stage renal disease (ESRD), patients on maintenance dialysis, or kidney transplant recipients. 3.AKI clearly caused by post-renal obstruction (e.g., calculi, tumor compression). 4.Pregnant or lactating women. 5.Patients with severely incomplete clinical data.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum Creatinine (Scr) Blood Urea Nitrogen (BUN);FBP1 Protein Expression Level; | — |
Secondary
| Measure | Time frame |
|---|---|
| Demographics, history (medical and medication), KDIGO stage, serial serum creatinine and BUN, plus outpatient follow-up values; | — |
Countries
China
Contacts
The First Affiliated Hospital of the Baotou Medical College of Inner Mongolia University of Science and Technology