Trigeminal neuralgia, hemifacial spasm and other diseases that are clinically diagnosed and meet the surgical indications for microvascular decompression (MVD), and require MVD as the definitive therapeutic intervention.
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Trigeminal neuralgia, hemifacial spasm and other diseases that are clinically diagnosed and meet the surgical indications for microvascular decompression (MVD), and require MVD as the definitive therapeutic intervention. 2. Age between 18 and 75 years. 3. The patient or their legal guardian signs the informed consent form and is willing to cooperate with all assessments, examinations, and follow-up during the study. 4. Preoperative vital signs are stable, with no severe dysfunction of vital organs such as the heart, liver, or kidneys. 5. No use of medications that may affect gastrointestinal function (such as antiemetics, prokinetic agents, etc.) for more than 1 week prior to surgery.
Exclusion criteria
Exclusion criteria: 1. Complicated with other severe neurological diseases (e.g., brain tumor, cerebrovascular malformation, etc.) that may interfere with the evaluation of nausea and vomiting; 2. Having severe mental illness or cognitive impairment, unable to cooperate with the research procedures; 3. With frequent nausea and vomiting symptoms before surgery; 4. A history of abdominal surgery within the recent 3 months; 5. Having hypersensitivity or contraindications to anesthetic drugs; 6. Being a pregnant or lactating woman.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Basic information: age, gender, height, weight, BMI, smoking history, drinking history, etc; | — |
Secondary
| Measure | Time frame |
|---|---|
| Medical history: hypertension, diabetes, history of motion sickness, gastrointestinal diseases, etc.; | — |
Countries
China
Contacts
The Second Affiliated Hospital of Wenzhou Medical University