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Construction and Validation of a Machine Learning-Based Prediction Model for Postoperative Nausea and Vomiting After Microvascular Decompression

Construction and Validation of a Machine Learning-Based Prediction Model for Postoperative Nausea and Vomiting After Microvascular Decompression

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600130333
Enrollment
Unknown
Registered
2026-08-18
Start date
2026-08-18
Completion date
Unknown
Last updated
2026-08-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Trigeminal neuralgia, hemifacial spasm and other diseases that are clinically diagnosed and meet the surgical indications for microvascular decompression (MVD), and require MVD as the definitive therapeutic intervention.

Interventions

Sponsors

The Second Affiliated Hospital of Wenzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Trigeminal neuralgia, hemifacial spasm and other diseases that are clinically diagnosed and meet the surgical indications for microvascular decompression (MVD), and require MVD as the definitive therapeutic intervention. 2. Age between 18 and 75 years. 3. The patient or their legal guardian signs the informed consent form and is willing to cooperate with all assessments, examinations, and follow-up during the study. 4. Preoperative vital signs are stable, with no severe dysfunction of vital organs such as the heart, liver, or kidneys. 5. No use of medications that may affect gastrointestinal function (such as antiemetics, prokinetic agents, etc.) for more than 1 week prior to surgery.

Exclusion criteria

Exclusion criteria: 1. Complicated with other severe neurological diseases (e.g., brain tumor, cerebrovascular malformation, etc.) that may interfere with the evaluation of nausea and vomiting; 2. Having severe mental illness or cognitive impairment, unable to cooperate with the research procedures; 3. With frequent nausea and vomiting symptoms before surgery; 4. A history of abdominal surgery within the recent 3 months; 5. Having hypersensitivity or contraindications to anesthetic drugs; 6. Being a pregnant or lactating woman.

Design outcomes

Primary

MeasureTime frame
Basic information: age, gender, height, weight, BMI, smoking history, drinking history, etc;

Secondary

MeasureTime frame
Medical history: hypertension, diabetes, history of motion sickness, gastrointestinal diseases, etc.;

Countries

China

Contacts

Public ContactWu Ying

The Second Affiliated Hospital of Wenzhou Medical University

1916900035@qq.com+86 577 85676708

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Sep 19, 2026