Hyperlipidemic Acute Pancreatitis
Conditions
Interventions
Sponsors
Ningbo No.2 Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for hyperlipidemic acute pancreatitis (HLAP): a. Satisfy the diagnosis of acute pancreatitis (acute abdominal pain plus serum amylase/lipase >= 3 times the upper limit of normal, or abdominal CT showing pancreatitis-associated changes); b. Serum triglyceride (TG) >= 11.3 mmol/L, or serum chylomicronemia with TG ranging from 5.65 to 11.3 mmol/L, and biliary, alcoholic and other etiologies are excluded. 2. Aged 18 to 80 years old (inclusive). 3. Patients admitted to the Emergency Intensive Care Unit (EICU) of our hospital within 24 hours after onset. 4. Written informed consent signed by the patient or their legal representative.
Exclusion criteria
Exclusion criteria: 1. Pancreatitis caused by combined other etiologies (e.g., cholelithiasis, alcoholic intoxication, drug-induced pancreatitis, traumatic pancreatitis, etc.). 2. Previous history of chronic pancreatitis or pancreatic surgery. 3. Complicated with advanced malignant tumors, severe immunodeficiency diseases, end-stage hepatic and renal failure. 4. Pregnant or lactating women. 5. Expected hospital stay less than 72 hours, or extremely high risk of loss to follow-up during follow-up period (e.g., no stable contact information). 6. Subjects who refuse to participate in this study or cannot cooperate to complete follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| blood lipid parameters;death;length of ICU stay;total hospital stay; | — |
Secondary
| Measure | Time frame |
|---|---|
| Organ failure (cardiac, pulmonary and renal);The 3-month readmission rate and case-fatality rate after hospital discharge were recorded.;rate of pancreatic necrosis;Incidence of infectious complications (pancreatic abscess, sepsis); | — |
Countries
China
Contacts
Public ContactQi Zheng
Ningbo No.2 Hospital
Outcome results
None listed