Allergic rhinitis
Conditions
Interventions
Healthy control:None
Sponsors
The First Affiliated Hospital of Xi 'an Jiaotong University Yulin Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Male or female subjects aged >=18 and =18 and <=65 years old; 6. Control group: individuals without the aforementioned allergic rhinitis symptoms.
Exclusion criteria
Exclusion criteria: 1.Patients with malignant tumors; 2.Pregnant or lactating women; 3.Subjects with severe underlying diseases involving the liver, kidney, heart, hematopoietic system, nervous system or psychiatric disorders; 4.Any other conditions deemed inappropriate for enrollment by the investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Allergen-induced mast cell activation assessment;Identification and characterization of IgE-binding allergens from Artemisia ordosica pollen;Diagnostic performance of component-resolved allergen-specific IgE detection;Immunoreactivity evaluation of recombinant major Artemisia ordosica pollen allergens; | — |
Secondary
| Measure | Time frame |
|---|---|
| Integrated transcriptomic and proteomic analysis for mechanism exploration;Peripheral immune profile and IgE-associated inflammatory characteristics;Immunomodulatory effects of hypoallergenic allergen immunotherapy candidates;Analytical performance and consistency evaluation of allergen-specific IgE detection methods; | — |
Countries
China
Contacts
Public ContactHao Wendong
The First Affiliated Hospital of Xi 'an Jiaotong University Yulin Hospital
Outcome results
None listed