Osteoarthritis
Conditions
Interventions
Experimental Group:Distal-oriented Rehabilitation
Sponsors
Affiliated Hospital of Shandong University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 60 years; 2. Able to walk independently for at least 10 meters (no walking aids required); 3. Berg Balance Scale score >= 40 points; 4. Mini-Mental State Examination (MMSE) Chinese version score >= 24 points, normal cognitive function; 5. Able to understand and sign a written informed consent form; 6. Meets the diagnostic criteria for one of the following groups, as described below: a. Healthy Control Group (HC): No significant history of lower back or lower limb pain, ODI = 50 points, no significant degenerative changes on imaging; b. Lower Limb Degeneration Group (LD): Clear clinical diagnosis of lower limb degenerative diseases (such as knee osteoarthritis with Kellgren-Lawrence grading >= 2, or hip degeneration with MRI showing cartilage thinning and osteophyte formation), but no moderate to severe lumbar degeneration (such as Pfirrmann grade = III); c. Spinal Degeneration Group (SD): Imaging showing lumbar degenerative changes (such as disc degeneration with Pfirrmann >= IV, facet joint hypertrophy, spinal stenosis, etc.), and a history of chronic low back pain for >= 3 months, ODI >= 20%; but no moderate or severe lower limb joint degeneration (such as knee osteoarthritis with Kellgren-Lawrence grading = 2); d. Complex Degeneration Group (CD): Meets both criteria of group b and group c, that is, clinical diagnosis of degeneration in both the lumbar spine and lower limbs.
Exclusion criteria
Exclusion criteria: 1. Central or peripheral nervous system disorders (such as stroke, Parkinson's disease, peripheral neuropathy, etc.); 2. History of lumbar spine surgery or lower limb joint replacement surgery; 3. Presence of exercise contraindications, such as severe osteoporosis, recent unhealed fractures, severe cardiopulmonary insufficiency, etc.; 4. Presence of psychiatric disorders affecting compliance (such as severe depression, anxiety, etc.); 5. Currently participating in other clinical intervention trials; 6. Other conditions deemed inappropriate for participation in this study by the clinical evaluator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Continuous Relative Phase;Muscle Synergy Index;Cortical activation level; | — |
Secondary
| Measure | Time frame |
|---|---|
| Maximum Lyapunov Exponent;Gait spatiotemporal parameters;Oswestry Disability Index;Pain score; | — |
Countries
China
Contacts
Public ContactLiu Kun
Affiliated Hospital of Shandong University of Traditional Chinese Medicine
Outcome results
None listed