Post-cesarean analgesia
Conditions
Interventions
Transversus abdominis plane block group:Transversus abdominis plane block with liposomal bupivacaine
Quadratus lumborum block group:Quadratus lumborum block with liposomal bupivacaine
Sponsors
The Third Xiangya Hospital Central South University
Eligibility
Sex/Gender
Female
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1.Scheduled to undergo elective cesarean delivery under single-shot spinal anesthesia; 2.Normal singleton pregnancy at =37 weeks of gestation; 3.Aged >18 and <55 years; 4.American Society of Anesthesiologists (ASA) physical status I or II; 5.Able to tolerate standard spinal anesthesia.
Exclusion criteria
Exclusion criteria: 1.Contraindications to neuraxial or regional anesthesia; 2.Allergy or intolerance to any study medication, such as sufentanil, ropivacaine, liposomal bupivacaine, or nonsteroidal anti-inflammatory drugs; 3.Body mass index (BMI) >40 kg/m²; 4.Body weight <40 kg in early pregnancy, based on the weight recorded at the 12-week antenatal visit, to exclude malnutrition or metabolic abnormalities; 5.Preeclampsia; 6.A history of chronic pain or regular opioid use; 7.Inability to understand the rating scales or cooperate with study assessments; 8.Conversion from neuraxial anesthesia to general anesthesia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cumulative PCA sufentanil consumption at 24 h after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to first postoperative flatus;Postoperative pain scores at rest, during movement, and during uterine contractions;Postoperative quality of recovery score;Cumulative postoperative consumption of nonsteroidal anti-inflammatory drugs;Incidence of postoperative adverse events;Incidence of postoperative nausea and vomiting;Time to first postoperative ambulation;Cumulative PCA sufentanil consumption at 48 h after surgery; | — |
Countries
China
Contacts
Public ContactMinghua Chen
The Third Xiangya Hospital Central South University
Outcome results
None listed