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A multimodal artificial intelligence-based predictive model for immunotherapy efficacy in biliary tract cancer and exploration of its underlying mechanisms.

A multimodal artificial intelligence-based predictive model for immunotherapy efficacy in biliary tract cancer and exploration of its underlying mechanisms.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600129896
Enrollment
Unknown
Registered
2026-08-11
Start date
2026-08-15
Completion date
Unknown
Last updated
2026-08-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Biliary Tract Cancer

Interventions

Sponsors

Yantai Yuhuangding Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Patients with pathologically confirmed biliary tract cancer; 2.Patients who had received at least two cycles of immunotherapy, with efficacy evaluations performed every two cycles according to the Response Evaluation Criteria in Solid Tumors (RECIST v1.1); 3.Patients with complete pre-treatment clinical information, complete MRI images, and complete pathological whole-slide imaging (WSI) data; 4.Patients with no history of other primary malignancies; 5.Patients aged >=18 years and <= 80 years at the time of diagnosis.

Exclusion criteria

Exclusion criteria: 1.Patients with other primary malignancies; 2.Patients with severe autoimmune diseases or organ failure that may interfere with the assessment of treatment efficacy; 3.Patients who discontinued immunotherapy due to non-progressive causes.

Design outcomes

Primary

MeasureTime frame
Overall Survival (OS);Objective Response Rate (ORR);Progression-Free Survival (PFS);Disease Control Rate (DCR);Area Under the Curve;Concordance index;

Countries

China

Contacts

Public ContactLiu Aina

Yantai Yuhuangding Hospital

nana4312@sina.com+86 535 6024907

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Sep 19, 2026