Dry Eye and Asthenopia
Conditions
Interventions
Severe group(Evaluation of dry eye symptom severity in subjects via the Ocular Surface Disease Index):None
Asymptomatic/mild group:None
Sponsors
Eye Hospital, Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1.Aged between 18 and 40 years, irrespective of gender. 2.Able to complete questionnaires and all scheduled examinations as required. 3.Spherical equivalent less than -6.00 D (myopia <6.00 diopters). 4.Voluntarily enroll in the study with signed written informed consent obtained.
Exclusion criteria
Exclusion criteria: 1.History of ocular or eyelid surgery within 6 months prior to enrollment. 2.History of contact lens wear within one month before enrollment. 3.Ocular diseases interfering with outcome evaluation, including active ocular infection, allergic conjunctivitis, uveitis, glaucoma, etc. 4.Presence of significant corneal lesions, severe blepharitis, or other ocular surface disorders precluding completion of examinations. 5.Use of any medications likely to interfere with dry eye conditions. 6.Pregnant or lactating women, as well as women of child-bearing potential who cannot use effective contraception during the study period. 7.Patients with psychiatric disorders or cognitive impairment; 8.Patients with high anisometropia;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The severity of dry eye symptoms; | — |
Secondary
| Measure | Time frame |
|---|---|
| accommodative response;Accommodative lag;High-frequency component of accommodative microfluctuation (HFC);Tear film breakup time (BUT);Visual Fatigue Questionnaire score;Lid margin- and meibomian gland-related parameters;Fluorescein sodium staining; | — |
Countries
China
Contacts
Public ContactLiang Lin
Eye Hospital, Wenzhou Medical University
Outcome results
None listed