Spontaneous Intracerebral Hemorrhage
Conditions
Interventions
Neuroendoscopy group:None
Sponsors
Huashan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age = 18 years; 2. Computed tomography (CT)–confirmed supratentorial spontaneous intracerebral hemorrhage (sICH); 3. Underwent either neuroendoscopic hematoma evacuation or conventional craniotomy for hematoma removal; 4. Postoperative hospital stay of at least 7 days; 5. At least 4 recorded measurements of complete blood count and C-reactive protein (CRP) within postoperative days 1–7; 6. Completed 90-day follow-up with modified Rankin Scale (mRS) assessment.
Exclusion criteria
Exclusion criteria: 1. Secondary intracerebral hemorrhage attributable to cerebral vascular malformation, intracranial aneurysm, brain tumor, cerebral venous sinus thrombosis, moyamoya disease, traumatic brain injury, hemorrhagic transformation after ischemic stroke, or other identified secondary etiologies; 2. Concurrent end-stage malignancy, severe cardiopulmonary, hepatic, or renal failure, or other conditions that substantially affect survival prognosis; 3. Underwent external ventricular drainage or decompressive craniectomy alone, without concomitant evacuation of intraparenchymal hematoma; 4. Presence of active systemic infection (e.g., severe pneumonia, urinary tract infection) prior to admission, or major surgery within 2 weeks before symptom onset; 5. Coexisting severe autoimmune disease, hematologic disorder, or malignancy, or long-term use of immunosuppressants or corticosteroids; 6. Pre-existing severe neurological disability, defined as a pre-stroke modified Rankin Scale (mRS) score =3; 7. Critically missing baseline clinical or imaging data; 8. Documented nosocomial infection occurring within postoperative days 1–7, as per the U.S. CDC/NHSN surveillance definitions (2024 edition).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Modified Rankin Scale (mRS) score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative systemic inflammatory trajectories; | — |
Countries
China
Contacts
Public ContactWu Biwu
Huashan Hospital, Fudan University
Outcome results
None listed