Idiopathic sudden sensorineural hearing loss,ISSNHL
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Meets the diagnostic criteria for idiopathic sudden hearing loss according to the "Guidelines for the Diagnosis and Treatment of Sudden Deafness": sudden, unexplained sensorineural hearing loss within 72 hours, with a hearing drop of >=20 dBHL at two consecutive frequencies; pure-tone audiometry types include flat loss or total deafness (hearing loss across all frequencies); 2. Hospitalized in the ENT department of our hospital for standardized treatment; 3. After treatment, follow-up pure-tone audiometry is done, with complete hearing follow-up results available to assess hearing recovery prognosis.
Exclusion criteria
Exclusion criteria: 1. There are conductive problems in the middle ear (like otitis media, eardrum perforation, otosclerosis, etc.), with an air-bone gap >10dB indicated by tympanometry; 2. There are clear secondary causes of hearing loss: acoustic neuroma, head trauma, exposure to ototoxic drugs, Ménière's disease, or congenital permanent hearing impairment; 3. Accompanied by end-stage liver or kidney failure, malignant tumors, congenital bleeding disorders, or autoimmune inner ear disease; 4. Interrupted standard treatment during hospitalization or discharged early before completing the standard care process.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| After one course of treatment (7 days), the improvement in average pure-tone audiometry (PTA) threshold at outpatient follow-up; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood clotting test indicators;Blood lipid indicators; | — |
Countries
China
Contacts
The First Affiliated Hospital of Dalian Medical University