Pulmonary tuberculosis-associated hemoptysis
Conditions
Interventions
Early pituitrin use group (Use of pituitrin within 12 hours after the index hemoptysis event):None
Non-pituitrin conservative treatment group (No use of pituitrin within 12 hours after the index hemoptysis event, with other conservative treatments provided):None
Sponsors
The Third People’s Hospital of Shenzhen
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged >= 18 years. 2. Hospitalized during the study period, with medical records documenting hemoptysis, blood-streaked sputum, or a hemoptysis-related diagnosis. 3. Diagnosed with active pulmonary tuberculosis, pulmonary parenchymal tuberculosis, or endobronchial tuberculosis, or judged by the investigators to have hemoptysis closely related to active tuberculosis or post-tuberculosis airway/parenchymal lesions. 4. A traceable index hemoptysis event and relevant clinical management records are available. 5. Medical records are sufficient to ascertain the main exposure, primary outcome, and key confounders.
Exclusion criteria
Exclusion criteria: 1. Patients who had previously explicitly refused the use of their clinical data for research. 2. Patients whose hemoptysis is judged by the investigators to be primarily caused by non-tuberculosis etiologies. 3. Pregnant patients. 4. Patients with missing key timing information, precluding ascertainment of time zero, the exposure window for pituitrin, or the 48-hour primary outcome. 5. Patients who underwent immediate bronchial artery embolization, surgery, tracheal intubation, or ICU rescue after the index hemoptysis event without a definable initial conservative treatment phase. 6. Patients participating in an interventional clinical trial that explicitly specifies hemostatic treatment for hemoptysis or restricts the use of pituitrin.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Net clinical success rate within 48 hours after the index hemoptysis event;Length of hospital stay; | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical hemostatic success rate within 24 hours;Time to cessation or marked reduction of hemoptysis;Rate of treatment escalation during hospitalization;Hemoptysis recurrence within 7 days;Hemoptysis recurrence within 30 days; | — |
Countries
China
Contacts
Public ContactLiang Fu
The Third People’s Hospital of Shenzhen
Outcome results
None listed