Diabetic Nephropathy
Conditions
Interventions
Diacylglycerol Oil Intervention Group:Replace the oil from the stir-fry with the product provided - 80% diglyceride cooking oil
Sponsors
Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Patients diagnosed with type 2 diabetes according to the 1999 WHO criteria; 2.Diagnosed as stage three diabetic nephropathy using the Mogensen classification; 3.Patients who have been ruled out for kidney damage caused by other reasons; 4.Patients have stably taken medication for at least one month prior to the intervention period and will not adjust medication during the three-month intervention period, with SGOT2 already used for three months; 5. Patients have been using ACEI/ARB for at least one month.
Exclusion criteria
Exclusion criteria: 1.No long-term use of lipid metabolism-affecting drugs in the past 6 months; 2.Abuse of narcotics, psychoactive drugs, or cigarettes in the past 6 months; 3.Complications with diabetic gangrene, ketoacidosis, hyperosmolar coma, thyroid and adrenal diseases, or stress conditions such as trauma, surgery, and infections; 4.Presence of serious, life-threatening primary diseases of the cardiovascular, liver, kidney, or hematopoietic systems, or mental disorders; kidney damage caused by urinary stones, acute or chronic nephritis, pyelonephritis, or urinary tract infections, and primary hypertension; 5.Currently using systemic corticosteroids or nonfinasteride drugs affecting glucose metabolism; 6.Participation in other clinical trials in the past three months or currently participating; 7.Patients deemed unsuitable for the clinical trial for other reasons by the researchers.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Blood Pressure;Blood Lipids;Glycated Hemoglobin (HbA1c);Fasting Plasma Glucose (FPG);Fasting Insulin; | — |
Primary
| Measure | Time frame |
|---|---|
| Urine Microalbumin/Creatinine Ratio;Urinalysis;Serum Creatinine (Cr);Blood Urea Nitrogen ;Serum Uric Acid;Estimated Glomerular Filtration Rate (eGFR);Urine ß2-Microglobulin;24-Hour Urine Biochemistry;Urinary Microalbumin Excretion Rate (24-hour urine); | — |
Countries
China
Contacts
Public ContactYuanyuan Yan
Shanghai Jiao Tong University School of Medicine
Outcome results
None listed