Tuberculosis
Conditions
Interventions
Exosomal tuberculosis markers LAM/LprG from sera were detected and results were positive:None
Exosomal tuberculosis markers LAM/LprG from sera were detected and the results were negative:None
Sponsors
The Eighth Medical Center of PLA General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. The close contacts of patients with active tuberculosis were screened according to the criteria of WS288-2017 Tuberculosis Diagnosis and T_CHATA+008-2020; 2. People between the ages of 18 and 65; 3. People without received anti-tuberculosis treatment; 4. Subjects voluntarily participated in this study and signed informed consent.
Exclusion criteria
Exclusion criteria: 1. People with Allergy; 2. People with fever, infectious diseases during the program; 3. Patients with active tuberculosis, patients currently undergoing tuberculosis treatment and patients with old tuberculosis; 4. Patients with abnormal liver function, diabetics, and patients with immune system diseases (such as HIV); 5. Patients with severe chronic diseases (such as heart, brain, vascular diseases, chronic kidney diseases); 6. Suffering from encephalopathy, uncontrolled epilepsy and other progressive neurological diseases; 7. Suffering from severe eczema or other skin diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lipoarabinomannan, LAM;Lipoprotein G, LprG; | — |
Secondary
| Measure | Time frame |
|---|---|
| Induration of Tuberculin Skin Test;tuberculosis-specific IFN-? release results;The lesion of pulmonary tuberculosis; | — |
Countries
China
Contacts
Public ContactJingli Du
The Eighth Medical Center of PLA General Hospital
Outcome results
None listed