Chronic obstructive pulmonary disease
Conditions
Interventions
Observation group:None
Sponsors
The Second Hospital of Jiaxing
Eligibility
Sex/Gender
All
Age
40 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 40 years old; 2. Diagnosed as COPD according to GOLD criteria (FEV1/FVC < 70%); 3. Priority will be given to patients with at least one history of acute exacerbation within the past year (excluding this one). If it is difficult to obtain recurrent cases, patients with the first case (0 in the past year) will be included; 4. This hospitalization was due to AECOPD and met the discharge criteria; 5. Agree to provide sputum, blood, and fecal samples; 6. Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Combined with pulmonary tuberculosis, active pneumonia (chest imaging (X-ray or CT) showing new pulmonary consolidation or infiltrative shadows, accompanied by clinical manifestations of acute lower respiratory tract infection (such as fever, purulent sputum) and laboratory inflammatory evidence (significant increase in CRP and PCT), and requiring targeted anti-infective treatment) and other acute severe infections; 2. Combined with malignant tumors, immunodeficiency diseases, cardiovascular and cerebrovascular diseases, and other major illnesses; 3. Systematic use of immunosuppressants; 4. Unable to complete follow-up; 5. Pregnant or lactating women; 6. Patients who refuse informed consent; 7. The researcher believes that it is not suitable to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical recovery outcomes of patients 4 weeks after discharge; | — |
Countries
China
Contacts
Public ContactTao Feng
The Second Hospital of Jiaxing
Outcome results
None listed