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Investigation of the Regulatory Mechanism of Gut Microbiota and Its Metabolites in Elderly Sarcopenia Based on the 'Spleen-Fat-Muscle' Metabolic Theory

Investigation of the Regulatory Mechanism of Gut Microbiota and Its Metabolites in Elderly Sarcopenia Based on the 'Spleen-Fat-Muscle' Metabolic Theory

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600129688
Enrollment
Unknown
Registered
2026-08-07
Start date
2026-05-07
Completion date
Unknown
Last updated
2026-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sarcopenia

Interventions

Sarcopenia group:None

Sponsors

Guangdong Provincial Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1.Meet the diagnostic criteria for sarcopenia 2.No gender restrictions, aged between 60 and 85 years old 3.Clear consciousness, stable vital signs, and able to cooperate with the investigation 4.Able to independently complete the measurement of parameters such as walking speed and grip strength 5.Sign the informed consent form and voluntarily participate in this study

Exclusion criteria

Exclusion criteria: 1.Use of antibiotics, microecological agents, antineoplastic drugs, glucocorticoids, and immunosuppressive drugs in the past one month 2.Complicated with serious heart, brain, liver, kidney, malignant tumor, neuromuscular conduction disorders or muscle diseases, Patients with primary diseases such as hematopoietic system, acute phase of wasting diseases and endocrine system 3.Patients with mental diseases, psychological and behavioral abnormalities, severe cognitive impairment or communication difficulties, or patients who cannot cooperate with the diagnosis, treatment, management and investigation for other reasons 4.Failure to undergo body composition analysis: inability to stand independently, have a pacemaker implanted, or carry metal or electricity in the body Patients with sub-devices

Design outcomes

Primary

MeasureTime frame
Gut Microbiota;Short chain fatty acids (SCFAs) profile;Inflammatory mediator indicators;Lipid factors;Lipomuscle factor;Lipid-related indicators;Muscle factors;

Countries

China

Contacts

Public ContactWei Lin

Guangdong Provincial Hospital of Traditional Chinese Medicine

weilin22@126.com+86 136 3247 6783

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Aug 25, 2026