Functional Gastrointestinal Disorders
Conditions
Interventions
FGIDs Patient Group:None
Healthy Control Group:None
Sponsors
Hainan West Central Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: FGIDs Patient Group: 1. Aged 18-60 years, regardless of gender; inpatients and outpatients presenting at the Gastroenterology Department of our hospital, with a preliminary diagnosis of Functional Gastrointestinal Disorders (FGIDs) based on medical history and clinical symptoms. 2. Underwent complete gastroscopy and colonoscopy with no significant organic abnormalities; based on one-on-one clinical interviews and questionnaire surveys, the diagnostic results met the Rome IV criteria for at least one of the following functional gastrointestinal disorders: Irritable Bowel Syndrome (IBS), Functional Dyspepsia (FD), Functional Diarrhea (FDr), and Functional Constipation (FC). 3. Voluntarily agreed to participate in this study and signed the written informed consent form. Healthy Control Group: 1. Aged 18-60 years, regardless of gender; healthy individuals recruited from the Physical Examination Center of our hospital or the local community. 2. Underwent complete gastroscopy and colonoscopy with no significant organic abnormalities; based on one-on-one clinical interviews and questionnaire surveys, they did not meet the Rome IV criteria for any functional gastrointestinal disorders, and had no other digestive system diseases. 3. Voluntarily agreed to participate in this study and signed the written informed consent form.
Exclusion criteria
Exclusion criteria: Exclusion Criteria for FGIDs Patient Group: 1. Patients with severe cardiopulmonary dysfunction. 2. Patients with uncontrolled hypertension. 3. Patients with lactulose intolerance. 4. Pregnant or lactating women. 5. Patients with other severe diseases (including severe infection, severe cardiac, respiratory, renal, neuropsychiatric diseases, etc.) or complicated with active tumors. 6. Patients with psychiatric disorders that impede study cooperation, those unwilling to sign the written informed consent form, individuals concurrently enrolled in other clinical trials, as well as other patients deemed unsuitable for enrollment by the investigators. Exclusion Criteria for Healthy Control Group: 1. Individuals with severe cardiopulmonary dysfunction. 2. Individuals with uncontrolled hypertension. 3. Individuals with lactulose intolerance. 4. Pregnant or lactating women. 5. Individuals with other severe diseases (including severe infection, severe cardiac, respiratory, renal, neuropsychiatric diseases, etc.) or complicated with active tumors. 6. Individuals with psychiatric disorders that impede study cooperation, those unwilling to sign the written informed consent form, individuals concurrently enrolled in other clinical trials, as well as other individuals deemed unsuitable for enrollment by the investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hydrogen Concentration in Expired Breath; | — |
Secondary
| Measure | Time frame |
|---|---|
| Methane Concentration in Expired Breath; | — |
Countries
China
Contacts
Public ContactPeng Cheng
Hainan West Central Hospital
Outcome results
None listed