Breast cancer
Conditions
Interventions
Gold Standard:Postoperative histopathological examination of axillary lymph nodes (including pathological results from paraffin sections of sentinel lymph node biopsy and axillary lymph node dissectio
Sponsors
Northern Jiangsu People's Hospital
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1.Female patients with pathologically confirmed breast cancer by core needle biopsy or surgical biopsy; 2.unilateral disease with maximum tumor diameter (measured by 2D ultrasound) = 2 cm; 3.candidates for planned breast-conserving surgery or total mastectomy (radiotherapy will be administered after breast-conserving surgery); 4.voluntary acceptance of preoperative multimodal ultrasound examinations including conventional grayscale ultrasound, elastography, and percutaneous/intravenous contrast-enhanced ultrasound.
Exclusion criteria
Exclusion criteria: 1.Patients with multiple fused, fixed, highly suspected metastatic lymph nodes identified on preoperative ultrasound or physical examination; 2.patients with extensive multifocal or multicentric lesions, bilateral breast cancer, or distant metastasis; 3.patients with a prior history of breast cancer or previous chest radiotherapy; 4.pregnant or lactating women; 5.patients with known allergy to ultrasound microbubble contrast agents such as Sonovue; 6.patients who are unable to complete follow-up or refuse to sign the written informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diagnostic accuracy of multimodal ultrasound AI model for axillary lymph node metastasis prediction in breast cancer; | — |
Countries
China
Contacts
Public ContactXiong Chunjin
Northern Jiangsu People's Hospital
Outcome results
None listed