Pulmonary Embolism
Conditions
Interventions
Gold Standard:CT pulmonary angiography (CTPA)
Index test:Contrast-free pulmonary perfusion imaging using dynamic chest radiography (DCR)
Sponsors
China-Japan Friendship Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Be at least 18 years old 2. Clinically suspected pulmonary embolism (based on Wells score or clinical judgment) and planned to undergo CTPA examination; 3. Be able to hold one's breath for about 6 seconds. 4. Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Severe arrhythmia; 2. The quality of the scanned image is unsatisfactory, or thin-layer image processing cannot be carried out; 3. History of thoracic radiotherapy or postoperative thoracic surgery (such as pacemaker implantation) : 4. The research participants voluntarily requested to withdraw from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Specificity of 4D-CT perfusion imaging for diagnosing pulmonary embolism;Area Under the ROC Curve (AUC) of 4D-CT perfusion imaging for diagnosing pulmonary embolism;Sensitivity of 4D-CT perfusion imaging for diagnosing pulmonary embolism; | — |
Secondary
| Measure | Time frame |
|---|---|
| Agreement between 4D-CT perfusion imaging and CTPA in localization of pulmonary embolism;Inter-observer agreement for interpretation of 4D-CT perfusion imaging;Adverse event; | — |
Countries
China
Contacts
Public ContactXu Yanyan
China-Japan Friendship Hospital
Outcome results
None listed