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Mechanism of Transcutaneous Auricular Vagus Nerve Stimulation on Limb Motor Function in Patients during the Recovery Phase of Cerebral Infarction

Mechanism of Transcutaneous Auricular Vagus Nerve Stimulation on Limb Motor Function in Patients during the Recovery Phase of Cerebral Infarction

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600129566
Enrollment
Unknown
Registered
2026-08-06
Start date
2023-05-06
Completion date
Unknown
Last updated
2026-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebral infarction

Interventions

Experimental group:Transcutaneous auricular vagus nerve stimulation (taVNS) at the cymba conchae + conventional treatment
Control group:taVNS sham stimulation, conventional treatment group.

Sponsors

The Affiliated Hospital of Yunnan University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Patients who meet the diagnostic criteria for ischemic stroke according to the Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke (2018), confirmed by cranial MRI or CT 2. first-ever stroke 3.disease course < 6 months 4.motor dysfunction symptoms persisting for = 2 weeks. Clear consciousness, stable vital signs, no dementia or psychiatric disorders. No cognitive impairment, able to communicate normally with medical staff and cooperate with treatment. Willing to voluntarily participate in the study and provide signed informed consent.

Exclusion criteria

Exclusion criteria: 1.Non-ischemic stroke or limb motor dysfunction secondary to hemorrhagic transformation after infarction. 2.Cognitive impairment based on the Mini-Mental State Examination (MMSE): =17 points for illiterates, =20 points for primary school education, <24 points for junior high school education or above. 3.Severe cardiac, pulmonary, or renal dysfunction. 4.Consciousness disorders or psychiatric illness preventing cooperation with treatment and evaluation. 5.Contraindications to taVNS therapy (e.g., facial or auricular pain, recent ear trauma, metallic implants above the cervical level).

Design outcomes

Primary

MeasureTime frame
Motor Function Score;Life skills rating;

Secondary

MeasureTime frame
Cognitive function score;

Countries

China

Contacts

Public ContactLuo qiu

The Affiliated Hospital of Yunnan University

luoqiu-220@163.com+86 135 7718 4961

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Aug 25, 2026