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Studying the efficacy and safety of alfentanil in patients undergoing endoscopic ultrasound: a randomized controlled trial

Studying the efficacy and safety of alfentanil in patients undergoing endoscopic ultrasound: a randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600129526
Enrollment
Unknown
Registered
2026-08-06
Start date
2023-11-07
Completion date
Unknown
Last updated
2026-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastrointestinal cancer

Interventions

Alfentanil group:Intravenous slow injection of alfentanil 10 ug/kg followed by intravenous injection of propofol 1.5 mg/kg
Sufentanil group:Intravenous injection of sufentanil 0.1 ug/kg, followed by intravenous injection of propofol 1.5 mg/kg after 2 min

Sponsors

Hebei Province Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Patients to undergo endoscopic ultrasonography; 2. Age is 18~65 years old, and gender is not limited; 3. Body mass index (BMI) of 18 to 30 kg/m^2; 4. American Association of Anesthesiologists (ASA) grade I~II.

Exclusion criteria

Exclusion criteria: 1. Patients who refuse to participate in the trial; 2. Those with a history of severe cardiac, cerebral, pulmonary, hepatic, or renal diseases; LVEF 1.5 times the upper limit of normal or GFR 180 mmHg and/or diastolic blood pressure > 110 mmHg, or hypotensive patients with blood pressure 100 beats/min; 5. Patients with anemia; 6. Those suspected of abusing narcotic analgesics or sedatives; 7. Those predicted to have or with a history of difficult airway; 8. Those known to be allergic to the drugs to be used; 9. Pregnant or breastfeeding women; 10. Those who are uncooperative or unable to communicate.

Design outcomes

Primary

MeasureTime frame
Number of body movements;

Secondary

MeasureTime frame
Total propofol dosage;Modified Aldrete Score;Oxygen saturation in PACU;Time to discharge;

Countries

China

Contacts

Public ContactZhang Limin

Hebei Province Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine

azai2010@126.com+86 317 2175971

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Aug 25, 2026