Renal Ischemia Complicated With Inflammatory Bowel Disease
Conditions
Interventions
IBD with rental ischemia:None
IBD without rental ischemia:None
Sponsors
The First Affiliated Hospital of Army Medical University
Eligibility
Sex/Gender
All
Age
17 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Based on the European Crohn's and Colitis Organization (ECCO) or the current consensus on the diagnosis and treatment of IBD in China, combined with clinical, endoscopic, imaging, and histopathological results, patients diagnosed with IBD (CD or UC) are clearly identified; 2. The ischemic group needs to be diagnosed with renal cortical ischemia or renal infarction through abdominal enhanced CT during this hospitalization/onset period (imaging manifestations include wedge-shaped or segmental low enhancement/enhancement defect areas of renal parenchyma); 3. Prior to the diagnosis of ischemia (ischemia group) or matching node (control group), within a short period of time (such as within one month), have complete and qualified abdominal plain CT data, and the scanning range fully covers the third lumbar spine (L3) plane, for the extraction of opportunistic body components; 4. The obtained abdominal plain scan CT data should have a uniform and constant scanning tube voltage of 120 kVp (conventional abdominal standard tube voltage), and the scanning layer thickness reconstructed at L3 level should be <= 5.0 mm to minimize the interference of partial volume effect on pixel segmentation of muscle/fat junction area.
Exclusion criteria
Exclusion criteria: 1. Patients with other definite high-risk embolic diseases or history (e.g., cardiogenic embolism due to atrial fibrillation, known severe hereditary thrombophilia, aortic dissection, etc.); 2. Patients with severe primary renal disease (e.g., end-stage renal disease, severe diabetic nephropathy or hypertensive nephropathy requiring dialysis) that may cause abnormal baseline renal perfusion structure; 3. Patients with active malignant tumors (tumor cachexia may severely interfere with the true metabolic status of body composition); 4. Patients with severe artifacts at the abdominal CT L3 level (e.g., artifacts from metal implants), massive ascites, or missing images, which preclude accurate segmentation and extraction of skeletal muscle area, subcutaneous fat area, and visceral fat area (SMA, SFA, VFA).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Renal ischemia; | — |
Secondary
| Measure | Time frame |
|---|---|
| Subcutaneous Fat Area (SFA);Visceral Fat Area (VFA);Skeletal Muscle Area (SMA); | — |
Countries
China
Contacts
Public ContactDu Mingshan
The First Affiliated Hospital of Army Medical University
Outcome results
None listed